Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 11 - Jul 16
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
K9 Advantix II Flea, Tick & Mosquito Treatment & Prevention for Large DogsK9 Advantix II Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult
K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.
Key Features
-
K9 Advantix II treatment & prevention protects dogs from fleas, ticks, mosquitoes, biting flies and lice
-
Kills fleas within 12 hours of application
-
Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
-
Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
-
No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Large
Pet Lifestage
- 7 weeks and older
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.0 ★★★★★
Based on 2162 reviews
Sort
Product Reviews
★★★★★ 5
Works well!
Style: 16 oz
This stuff works well. I've only ever used it after my tires had been punctured and ran flat... I haven't had a flat this wouldn't seal... 3 uses so far all 3 have fixed flats and been many miles put on since the repairs. I start with as little as possible and if it doesn't seal I just add more, I think I've managed to use far less than recommended and successfully sealed punctures. I've only used it on fat tire e-bike tires. I'm pretty comfortable with the seal and I have no plans to replace the tubes, which saves me a fair amount of trouble. I will update if it springs any leaks without new punctures.
It's very easy to use and actually pretty clean especially compared to automotive type tire repair foams.
The first repair I used it for was a brand new bike that just wouldn't hold air in the rear, totally unsure what caused it to keep losing air but 2 or 3 small doses of slime fixed it.
The most recent slime repair, I had a wobbly bike ride which felt weird and I couldn't figure out why but a few hours after I had returned home both tires were totally flat. They both had a handful or more of some really heavy duty thorns stuck in the tire that likely barely punctured the tubes but the rear tire also had a roofing nail in it. I did not think the slime was going to fill that one, it was a pretty heavy leak once I removed the nail, but Slime did seal it and I've since ridden the bike twice and in the same rough conditions I normally would still holding strong at higher pressure than I normally ride, have yet to drop back down since refilling but I am hoping and expecting it won't be a problem.
Two thumbs up. I always keep a small tube in my bike bag and I am confident if I ever need it while I'm out and about it will be useful.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
★★★★★ 5
Who can live without slime great stuff and a good price. 👍
Style: 32 oz
If anyone has an outdoor anything that takes air. You should never be caught without this stuff. It seals your tires on almost anything and it lasts longer than you would expect. It’s easy to use and easy to clean up after using it. It will work well for anything that is supposed to hold air. Great product.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026
★★★★★ 5
Title: Reliable, Easy-to-Use, and Worth Every Penny
Style: 32 oz
I’ve been using Slime tire sealant for my fat tire e-bike, and I can say with confidence that this product delivers exactly what it promises. The application is simple, the results are consistent, and the peace of mind it provides is invaluable. For anyone who rides regularly — whether for commuting, recreation, or deliveries — this is a product that pays for itself many times over.
The first thing I appreciate about Slime is how easy it is to install. The bottle is well-designed, the instructions are clear, and the process takes just a few minutes. You simply deflate the tire, remove the valve core, squeeze in the recommended amount, reinstall the valve core, inflate, and spin the wheel to distribute the sealant evenly. No special tools, no mess, and no guesswork — just a straightforward, user-friendly process.
Performance-wise, Slime does exactly what it’s supposed to do: seal punctures quickly and effectively. I’ve had nails, thorns, and sharp debris puncture my tires while riding, and in every case where the leak was within the tread area, Slime sealed it instantly. There’s something incredibly reassuring about hearing that faint hiss of air for a second, then watching it stop as the sealant does its job. It’s a real-time reminder that this product is actively protecting you from being stranded.
What sets Slime apart from other sealants I’ve tried is its durability. Once applied, it stays active inside the tube for months, ready to respond to new punctures as they happen. It doesn’t dry out quickly, it doesn’t clump up, and it doesn’t cause balance issues with the tires. For someone who rides almost daily, that reliability is a huge plus.
Another thing I respect about this product is that it’s non-toxic and environmentally friendly. If a bit of sealant escapes during a repair, I don’t have to worry about it harming the environment. It’s also water-soluble, making cleanup easy if I ever need to replace a tube or tire. That attention to safety and sustainability shows that the company isn’t just making a great product — they’re doing it responsibly.
The value for the price is excellent. One bottle goes a long way, and when you factor in the cost of replacing tubes, paying for roadside repairs, or even the inconvenience of being late because of a flat, Slime is an investment in both savings and peace of mind. For delivery riders like me, it’s especially valuable — every flat avoided means another day of work uninterrupted.
In short, Slime is one of those rare products that I can recommend without hesitation. It’s easy to use, effective, long-lasting, and backed by a company that clearly understands the needs of cyclists and e-bike riders. It has already saved me from countless headaches, and I plan to keep a bottle on hand at all times. If you ride regularly and haven’t tried it yet, you’re taking an unnecessary risk — this is one of the best preventative tools you can add to your maintenance kit.
Verdict: Five stars for performance, ease of use, and overall value. Slime is a must-have for any serious rider who values reliability and wants to keep rolling no matter what’s on the road.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 11, 2025
★★★★★ 4
Slime is good, pump is a disaster
Style: 1 gal, Style: 1 gal
The only reason I am giving this a 4 star(not zero) rating is the slime itself. The actual pump on the 1 gallon canister is awful. It makes so much mess, so I do not know whether I pumped the slime into the tubes or it all just spilled out of the base of the pump. The bottles worked great, but this time I needed to use more slime for a bunch of tires. What a slimy mess that was. Very poor pump design. Only after I spilled who knows how much of the slime, I finally washed it and was able to see the problem. The cap at the base of the pump got unscrewed and let all the slime lose. I screwed it back up and this should fix the mess next time I use it. Just a heads if someone encounters the same issue.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 22, 2026
★★★★★ 5
Great product
Style: 16 oz
Worked as advertised. I would order again.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
recommand products
NZXT Accessory MM-MXLSP-GR Mousemat XL Grey Retail
32.49
TITANIUM CLUTCH COVER BOLTS (6) RZR 900/1000 by ZRP (Zollinger)
99.99
Yuzu Cat Enamel Pin
15.00
Can-Am X3 (all models) Adjustable Rear Sway Bar Links by Shock Therapy
174.95
Polaris RZR 900 Expedition Rack (Jim Todd Edition) - by Razorback Offroad
750.00