USP14 His Tag Protein, Human
SKU: 95881344823

USP14 His Tag Protein, Human

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Description

USP14 His Tag Protein, HumanProduct Specification Species Human Synonyms Ubiquitin carboxyl terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin specific processing protease Accession P54578 Amino Acid Sequence Pro2 Gln494

Product Specification


Species Human
Synonyms Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease
Accession P54578
Amino Acid Sequence

Pro2-Gln494 PLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQGGGSHHHHHHHH

Expression System Baculovirus-InsectCells
Molecular Weight 58kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Liquid
Storage Buffer 20mM Hepes, 100mM NaCl, 10%Glycerol, 3mMDTT pH8.0
Stability & Storage

·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Reference

Front Pharmacol. 2022 Jan 5:12:801328. J Cell Physiol. 2021 May;236(5):3396-3405. Epub 2020 Nov 1.

Background

Ubiquitin-specific protease 14 (USP14), a deubiquitinating enzyme (DUB), is associated with proteasomes and exerts a dual function in regulating protein degradation. USP14 protects protein substrates from degradation by removing ubiquitin chains from proteasome-bound substrates, whereas promotes protein degradation by activating the proteasome. Increasing evidence have shown that USP14 is involved in several canonical signaling pathways, correlating with cancer, neurodegenerative diseases, autophagy, immune responses, and viral infections. The activity of USP14 is tightly regulated to ensure its function in various cellular processes. Due to its intriguing roles in the stabilization of disease-causing proteins and oncology targets, USP14 has garnered widespread interest as a therapeutic target.

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Exchange/Return Notes
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SKU: 95881344823

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4.9 ★★★★★
Based on 446 reviews
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Product Reviews
A
Verified Purchase
Alicia Ring Thomas
Lake Worth, US
★★★★★ 5
Nice
Really nice provide. Not too large. Holds 3 passports comfortably— 4 tightly
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 7, 2025
T
Verified Purchase
Tex
Carnegie, US
★★★★★ 4
Great for keeping family passports organized while traveling
I bought this for our family’s recent trip to Europe after struggling on a previous trip to keep track of everyone’s passports. Last year I was constantly worried about losing one or forgetting where I put them, so having everything in one place made a huge difference this time. This holder fit all four passports perfectly and still had room for cards and even a spot where I could clip my keys inside. It ended up being one of those things I used constantly throughout the trip at airports, hotels, train stations, and checkpoints. As long as I had the case with me, I felt confident all four passports were where they needed to be. The material feels durable enough for travel, and the zipper worked smoothly the whole trip. The black color also looks clean and professional without standing out too much. Pros: Holds four passports comfortably Helped keep travel documents organized Durable feel and smooth zipper Extra storage for cards, cash, or keys Lightweight enough for travel Gave me peace of mind during a busy international trip Cons: Slightly bulkier than necessary for minimalist travel Could be slimmer for people who only want passport storage without extra pockets
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 13, 2026
B
Becca
Lowell, US
★★★★★ 5
Great passport holder
I really like this family passport holder. This is the second one I buy since we travel with our kids internationally at least once a year. It’s a good way to keep document organized and on the ready. I like that it has space for four passport books, plus ID’s and cards. It also has a pen holder. And a couple zippered pockets. We also travel with our dogs and this case kept all our family’s and pet’s documents in one convenient place. It’s also easy to use. The zipper is easy to open and close. And I like that the strap is not on the zipper. The last holder I got has the strap on the zipper and when you opened it things could fall off if you weren’t super careful. I like that little pocket on the front. It’s convenient to keep boarding passes handy. The quality is great too. I didn’t even read about it being fire proof but that just makes it nicer. And it’s pretty easy to keep clean because the material can be just wiped down and doesn’t stain easily. We just keep or passports there and put them on our document area at home. So they’re ready to go whenever we need. Overall a great product small families traveling.
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Reviewed in the United States on February 12, 2025
C
Christina
Draper, US
★★★★★ 5
Great passport storage for a family of 4!
This passport travel wristlet was perfect of or family of 4 to use while traveling. It was large enough to keep all of of our passports inside and also travel documents. I love that the material is fire resistant, but the material is slightly tacky b/c of that. Not a big deal for me, but something worth noting. I don't mind the material b/c it gives me peace of mind when storing my passports inside that if there is a fire, our passports will be protected. Overall, I think this is a great option to safely store and travel with your passports!
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Reviewed in the United States on April 22, 2025
V
Verified Purchase
VMathew
Lexington, US
★★★★★ 4
Mr
Good
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 25, 2026

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