STAT6 His&Strep Tag Protein, Human
SKU: 14030093284

STAT6 His&Strep Tag Protein, Human

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Description

STAT6 His&Strep Tag Protein, HumanProduct Specification Species Human Synonyms STAT6C,STAT6B, interleukin 4 induced,IL 4 STAT,D12S1644 Accession P42226 1 Amino Acid Sequence Met1 Trp847 with His&Strep Tag at the C Terminus Expression System Baculovirus InsectCells Molecular Weight 95 110kDa (Reducing) Purity 95% by SDS PAGE & > 90% SEC HPLC Conjugation Unconjugated Tag His Tag, Strep Tag Physical Appearance Liquid Storage Buffer 50mM Hepes,200mM NaCl,20%Glycerol,1mM DDT Stability &

Product Specification


Species Human
Synonyms STAT6C,STAT6B, interleukin-4 induced,IL-4-STAT,D12S1644
Accession P42226-1
Amino Acid Sequence

Met1-Trp847 with His&Strep Tag at the C-Terminus
Expression System Baculovirus-InsectCells
Molecular Weight

95-110kDa (Reducing)
Purity ＞95% by SDS-PAGE & > 90% SEC-HPLC
Conjugation Unconjugated
Tag His Tag, Strep Tag
Physical Appearance Liquid
Storage Buffer

50mM Hepes,200mM NaCl,20%Glycerol,1mM DDT
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Karpathiou G, Papoudou-Bai A, Ferrand E, Dumollard JM, Peoc'h M. STAT6: A review of a signaling pathway implicated in various diseases with a special emphasis in its usefulness in pathology. Pathol Res Pract. 2021 Jul;223:153477.
2.Chao H, Zheng L, Hsu P, He J, Wu R, Xu S, Zeng R, Zhou Y, Ma H, Liu H, Tang Q. IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation. JCI Insight. 2023 Mar 22;8(6):e157091.

Background

STAT6 (Signal Transducer and Activator of Transcription 6) is a transcription factor that plays a pivotal role in the cellular response to interleukin-4 (IL-4). It is activated through IL-4-induced tyrosine phosphorylation. Its primary function is to mediate most of IL-4's effects, including promoting cell survival by inducing the expression of the anti-apoptotic gene BCL2L1/BCL-X(L). To activate transcription, STAT6 requires interaction with coactivator proteins like p300 and CBP. A key physiological characteristic is its direct interaction with NF-κB, which underlies the synergistic transcriptional activation observed between the IL-4 and NF-κB signaling pathways. Clinically, its central role in IL-4-mediated responses makes it a molecule of interest in immune-related processes.

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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 14030093284

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4.7 ★★★★★
Based on 1323 reviews
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Product Reviews
M
Verified Purchase
Mike
Charlottesville, US
★★★★★ 5
Works For Desired Use
Color: Black, Size: 4 Panel-136‘’W-Round Pad
I recently purchased the Room Divider 6FT Folding Privacy Screens, 4 Panel Partition Room Dividers, and I must say, it has transformed the way I use my living space. The four-panel design is both elegant and functional, providing instant privacy without feeling bulky or overwhelming in my room. Setting it up was a breeze; the folding mechanism is smooth, allowing me to adjust the configuration as needed—straight, angled, or zigzag. I particularly appreciate the sturdy build; the panels feel solid yet lightweight, making it easy to move around when I want to reconfigure my space. Aesthetically, it’s a great addition. The neutral finish blends well with my décor, and the simple design doesn’t draw too much attention while still offering a sense of separation. It’s perfect for creating a temporary office corner, dividing a studio apartment, or even using it as a backdrop for online meetings. If I had to point out a minor downside, it would be that the divider isn’t completely soundproof—so conversations can still carry through—but for visual privacy and space management, it’s excellent. Overall, I’m extremely satisfied and would recommend it to anyone looking for a versatile and stylish room divider.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 24, 2026
A
Verified Purchase
Ansley
Lowell, US
★★★★★ 5
True to size & Use a Drill
Color: Beige, Size: 3 Panel-102‘’-Round Pad, Color: Beige, Size: 3 Panel-102‘’-Round Pad
Love this! Works perfectly for where I wanted it. I did measure my room incorrectly and thought it would be smaller, thankfully it’s not and thankfully it’s not bigger than the room itself. I did like how the whole thing was move-able but it was a bit annoying so I just added extra clips to the left of the middle one and unscrewed the right of the middle at the bottom so it opens like a door, this did make it a bit flimsy but duck taping it to the wall as anchor it works. 100% recommend, but do suggest a drill and a second set of hands to put it together, due to its size it can be a bit difficult to maneuver putting together yourself. Also if you have a clingy cat like I do, and think this will help keep them out, no, my cat who is very large can manage to squeeze underneath it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 9, 2024
S
Verified Purchase
Sam
Carnegie, US
★★★★★ 1
waste of money
Color: Black, Size: 4 Panel-136‘’W-Round Pad
This is a total waste of money. Its only going to free stand if you arent moving it. If you are planning on dividing a room, and then folding these for space and then dividing the room again, itll last a few days. The poles kept coming off of the screws that holds the fabric on the poles together. Was fixing this EVERY DAY. Finally got tired of doing this and just threw it out. Lot of money spent on garbage. Get a sheet room divider, or something that isnt cheaply made. Was simply making an office type space in a bedroom, to seperate the two areas for work, and folding it kept making the poles come off those twisted screws. just not worth it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 3, 2026
A
Verified Purchase
Alysha H.
San Leandro, US
★★★★★ 5
Absolutely love this room divider!
Color: Beige, Size: 3 Panel-102‘’-Round Pad, Color: Beige, Size: 3 Panel-102‘’-Round Pad
When they say you can't see anything through it, they are correct. As you can see by the video, the cars are traveling by with the sunlight on the divider and you still can't see any cars passing nor can you see the ones in the parking lot. You can also tell it blocks out the sunlight too which is a definite plus for our store. Quality material on the divider. Material is nice and snug on the poles with no ripples. I also like the base of these, they make the divider nice and sturdy and can be adjusted if floor is uneven. Also the design of the legs allow them to go under your furniture. Also putting them together is pretty easy. Just make sure you when you are putting the poles together to make sure at the top of the pole that the indent screw hole faces out. This makes for a better look. The directions don't say which way to turn and at 1st, I had one, one way and the other was another way as both ways work that way but I wanted a uniform/better look.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 29, 2024
B
Verified Purchase
B. R. Grande
Whiting, US
★★★★★ 4
Works well, need power tool to assemble
Color: Beige, Size: 3 Panel-102‘’-Round Pad, Color: Beige, Size: 3 Panel-102‘’-Round Pad
Sturdy enough, especially when feet are positioned for balance. Works perfectly to create a WFH “cubicle”. Can adjust the size to provide complete privacy or fold back a panel when I want more openness. The fabric panels are not perfectly taught, but pretty close. The only negative is that without my husband’s power drill/screwdriver we wouldn’t have been able to put it together. It would take the strength of Thor to do it with just a manual screwdriver.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 30, 2022

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