PTK7/CCK4 His Tag Protein, Cynomolgus
SKU: 21095137772

PTK7/CCK4 His Tag Protein, Cynomolgus

Sale price$243.00 Regular price$270.00
Save 10%

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Jul 8 - Jul 13

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

PTK7/CCK4 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms PTK7, CCK4, Tyrosine protein kinase like 7, Protein tyrosine kinase 7, Protein tyrosine kinase 7 Accession A0A2K5VNI5 Amino Acid Sequence Ala39 Thr712, with C terminal His Expression System HEK293 Molecular Weight 90 100kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0.

Product Specification


Species Cynomolgus
Synonyms PTK7, CCK4, Tyrosine-protein kinase-like 7, Protein-tyrosine kinase 7, Protein-tyrosine kinase 7
Accession A0A2K5VNI5
Amino Acid Sequence Ala39-Thr712, with C-terminal His
Expression System HEK293
Molecular Weight 90-100kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Lichtig H. et al. (2019) Ptk7 proteolytic fragment proteins function during early xenopus development. Dev Biol. 453 (1): 48-55.

2、Damelin M. et al. (2017) A ptk7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions. Sci Transl Med. 9 (372): eaag2611.

3、Berger H. et al. (2017) Ptk7 faces the wnt in development and disease. Front Cell Dev Biol. 5: 31.

Background

PTK7 comprises an extracellular region with seven immunoglobulin (Ig)-like loops, a transmembrane domain, and a cytosolic region containing a defective tyrosine kinase catalytic domain. Previous studies have reported that PTK7 functions as a co-receptor in the semaphorin/plexin signaling pathway, as well as in planar cell polarity and non-canonical Wnt signaling pathways during developmental processes. Additionally, PTK7 is associated with tumorigenesis. The expression of PTK7, which is upregulated in various malignancies, is negatively correlated with disease-free survival and/or overall survival in patients with cancer. PTK7 potentiates oncogenic signaling by functioning as a co-receptor for active RPTKs, such as FGFR1. The expression of PTK7 is also upregulated in endothelial cells, especially during tube formation.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 21095137772

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.6 ★★★★★
Based on 1853 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
A
Verified Purchase
Ashley Driggers
Lowell, US
★★★★★ 5
Good Quality
Color: C-apricot, Size: 14 Inch
The quality of the backpack is very good. I like how it has a waterproof feeling fabric. I have used it for work and travel and it is excellent quality.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 12, 2026
T
Verified Purchase
Tara S
West Palm Beach, US
★★★★★ 5
Great Bag
Color: Black Brown, Size: 17.3 Inch
This backpack is awesome it holds way more than I anticipated and is super cute. The quality seems to be good to what I can tell.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 16, 2025
T
Verified Purchase
Teri Haselhorst
Draper, US
★★★★★ 5
Classy!
Love this! Classy looking and nice quality. Received many compliments on our trip.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 10, 2025
F
Verified Purchase
Felipe
Charlottesville, US
★★★★★ 5
Gran producto
Color: C-black, Size: 14 Inch
Muy buen producto. La calidad era la esperada.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 22, 2025
J
Verified Purchase
Joi
Lexington, US
★★★★★ 5
Very nice
Color: Green
It’s such a cute backpack! I’d get the beige color if using for work. The olive green can look a bit flashy in a corporate environment :( old people don’t know how to have fun
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026

recommand products