Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
IgG2 Fc His tag Protein, HumanProduct Specification Species Human Synonyms Ig gamma 2 chain C region, Ig gamma 2 chain C region DOT, Ig gamma 2 chain C region TIL, Ig gamma 2 chain C region ZIE Accession P01859 Amino Acid Sequence Glu99 Lys326(V161M, S257A), with C 10*His Expression System HEK293 Molecular Weight Theoretical: 27. 4kDa Actual: 32kDa Purity >90% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer 0.
Product Specification
| Species | Human |
| Synonyms | Ig gamma-2 chain C region, Ig gamma-2 chain C region DOT, Ig gamma-2 chain C region TIL, Ig gamma-2 chain C region ZIE |
| Accession | P01859 |
| Amino Acid Sequence | Glu99-Lys326(V161M, S257A), with C-10*His |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.4kDa Actual:32kDa |
| Purity | >90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.2 ★★★★★
Based on 523 reviews
Sort
Product Reviews
★★★★★ 4
Great budget multi tool
Style: Corded
Nice little rig that fits the bill for occasional hobby use. The motor is powerful enough to polish and cut without bogging down. Bits attach securely and easily. Light and easy to use. The price is great for this multi tool. Recommended
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 22, 2025
★★★★★ 5
Favorite DIY Sidekick
Style: Corded
Bought this for one task: grind away an interfering piece of metal in my door’s strike plate. I was unhappy about spending $20 on another DIY tool for one tiny specific purpose but to my pleasant surprise, I haven’t stopped using this dremel since.
I’ve cut and sanded wood projects, trimmed custom cabinet panels, smoothed jagged hole edges, and more. I hardly ever turn the dial past 4 to find a speed I’m comfortable with. It’s very powerful and gives great results. I bought a cheaper one that busted on the first try and I’m so happy this was my next choice. It’s handled all the fixer-upper challenges I’ve asked of it.
The starter kit is a little sparse on the good stuff like saw blades and washers but very helpful. The case is convenient. My only gripe is I have to be intentional about placement to get it to close but the cord and extension tool is so long and useful that it makes up for it. It’s a little bulky but comfortable to hold and I’ve been able to reach all the narrow corners and tight spaces I’ve needed.
My next project is to cut away some protruding screw threads and my immediate thought was to reach for the WEN rotary. For the amount of value I’ve gotten out of it, this thing has paid for itself a few times already.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 8, 2025
★★★★★ 5
Perfect rotary tool for light or heavy project with power.
Style: Corded, Style: Corded
Polishing is my main purpose for using rotary tool. I've had hardell and dremmel before. Heavy use of these tool they get hot and wear out fast. Wen rotary tool is better. It's heavy duty, twice as big, 1.5 lbs, it has big motor and variable speed without the noise.
It's perfect for hobbies and for 3in polishing or sanding pad. It's polarized electric plug in. The attachments came with it is superior than any rotary tool I've used. Its a solid product. I can already tell undoubtedly this is a good product if not the best. The other rotary tool have the lock chuck button opposite of the power button which premarturely damages internal mechanism accidentally use the lock button while still spinning. Wen is power button is switch away from chuck lock button. It's not too big nor too small to use. The life expectancy for Wen rotary tool will likely be three times longer than dremmel or hardell in my guess because of its design.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 13, 2026
★★★★★ 5
Love this thing. But, love the company even more!
Style: Corded
This is my 1st rotary tool ever. So excited because the things you can do are limitless.
I received my tool and only used it 3 times. I was so happy I bought this but then the power switch broke, oddly.
I said well, you get what you pay for right? Well, I called the phone number listed here on Amazon, and they answered. I briefly explained what happened, and just asked if I could send them the main unit for replacement. The customer service person asked for my details, order number, etc.
Then within a few minutes, he said, Sir, we're just going to send you a new one, if that's okay. I was like huh? I said, I know it's been 8 months and that really would be awesome because I love it!
He said we stand behind all of our products and it's the least we can do, and we apologize for any inconvenience.
I was like huh? Lol.
It really is hard to find service like this these days. To be so excited about a 20 dollar tool, that you've always wanted but just never got around to getting, spending 20 bucks and not only getting a fantastic tool, but getting the authentic service we all deserve, priceless!
Thank you so much Wen and Amazon! Hope this helps others that are interested in this really useful and fun tool.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 12, 2023
★★★★★ 3
Safety concerns
Style: Corded
The variable speed when base is nice and works very well. However the flexible accessory shaft has a major design flaw., there is no locking mechanism on the flexible shaft making it impossible to tighten the collet down to hold the bit in place. Making it easy for the bit to come out of the flexible shaft while it is rotating at any speed.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 3, 2026