IL-31 Protein, Human
SKU: 95487221873

IL-31 Protein, Human

Sale price$97.20 Regular price$108.00
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Description

IL-31 Protein, HumanProduct Specification Species Human Synonyms IL 31,IL31,Interleukin 31 Accession Q6EBC2 Amino Acid Sequence Ser24 Thr164 Expression System E. coli Molecular Weight 16kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM PB, 100mM NaCl, pH6. 5 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.

Product Specification


Species Human
Synonyms IL-31,IL31,Interleukin-31
Accession Q6EBC2
Amino Acid Sequence Ser24-Thr164
Expression System E.coli
Molecular Weight 16kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM PB, 100mM NaCl, pH6.5
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.J Allergy Clin Immunol. 2023 Jul 13;S0091-6749(23)00888-6. Online ahead of print.
2. Allergy. 2023 Jul 13. Online ahead of print.
3. Clin Exp Med. 2023 Jul 1. Online ahead of prin

Background

IL-31 which produced by activated Th2-type T cells. IL-31 signals through a receptor composed of IL-31 receptor A and oncostatin M receptor. IL-31 activates STAT3 and possibly STAT1 and STAT5 through the IL-31 heterodimeric receptor composed of IL31RA and OSMR. IL-31 has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. Patients with atopic dermatitis, chronic spontaneous urticaria, allergic contact dermatitis, prurigo nodularis, primary cutaneous lymphoma and mastocytosis exhibit increased serum levels of IL-31 protein and elevated IL-31 mRNA in the skin.

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Exchange/Return Notes
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SKU: 95487221873

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Courtney Cummins
Boise, US
★★★★★ 1
chewed up on 2 seconds
not durable at all. my red heeled mix had the stuffing out in less than 2 minutes
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 29, 2022
M
Verified Purchase
Michael J1S
Lexington, US
★★★★★ 5
Great toy but easy to extract the stuffing
Style: Hedgehog
Theyvare my dogs favorite but wish they'd last more than 3 months.
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Reviewed in the United States on April 27, 2026
K
Verified Purchase
kidhammer
New York, US
★★★★★ 5
Well loveed
Style: Hedgehog
Our Corgi loves this one.
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Reviewed in the United States on August 27, 2025
M
Verified Purchase
Meagan patterson
Whiting, US
★★★★★ 3
Not for puppies that like to chew
Style: Monkey
Tore really quickly
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Reviewed in the United States on November 12, 2025
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Verified Purchase
CMad
Draper, US
★★★★★ 1
DO NOT BUY THIS TOY FOR A DOG
Style: Hedgehog
I purchased this toy for my Mothers 11 pound female 10 years old rescue dog. Under 1 hour the dog chewed off all the feet, the nose, and then started to pull off the fur. We took it away. Dangerous!!! The description list for Aggressive Chewers it is not!!!
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Reviewed in the United States on December 17, 2024

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